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The Mutant Ratpack is the main antagonist force from the Battletoads series, appearing in all games. Commanded by the Dark Queen, the group is comprised of all manner of foul creatures which the Queen recruited from the universe over. Though most of their numbers are made up of mutant rats they also have pigs, snakes and other mutant vermin on their ranks.

The Dark Queen rules over the group, with her most trusted underlings, Big Blag and Robo-Manus, serving as her right-hands. The group also have other high-ranking underlings below those two, such as General Slaughter, General Vermin and Karnath.